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• Hepatocellular carcinoma (HCC) and LT Collaboration with the National HCC Registry. We are also collaborating with UCSF and the Radiodiagnostic Department to identify LT failure associated factors.
• Wilson’s disease: Collaboration with several national centers (IPPC and the “Mixed Rare Diseases Research Unit”)to perform cellular and genetic studies and generate a database to better understand this disease. Participation in trials.
• Non-cirrhotic and cirrhotic portal hypertension: The group belongs to the Spanish multicenter REHEVASC which aims to study this disease by creating a Spanish database and a bank of blood samples for possible future studies. Collaborations with national groups to improve the management of cirrhotic patients with portal hypertension and portal vein thrombosis.
• Non-alcoholic steatosis. Industry promoted studies. Clinical trials in liver transplant context. Participation in the Spanish registry. Collaboration in National guide.
• Cholestasic liver diseases: Industry promoted studies. Collaboration in the Spanish registry. Most relevant scientific articles
• Alvarez-Sotomayor D., Satorres C., Rodriguez-Medina B., Herrero I., De La Mata M., Serrano T. et al. Controlling Diabetes after Liver Transplantation: Room for Improvement. Transplantation. 2016;100(10): e66-e73.
• Manns M., Samuel D., Gane E.J., Mutimer D., McCaughan G., Buti M. et al. Ledipasvir and sofosbuvir plus ribavirin in patients with genotype 1 or 4 hepatitis C virus infection and advanced liver disease: a multicentre, open-label, randomised, phase 2 trial. The Lancet Infectious Diseases. 2016;16(6):685-697.
• Aguero F., Forner A., Manzardo C., Valdivieso A., Blanes M., Barcena R. et al. Human immunodeficiency virus infection does not worsen prognosis of liver transplantation for hepatocellular carcinoma. Hepatology. 2016;63(2):488-498.
• Addolorato G., Bataller R., Burra P., DiMartini A., Graziadei I., Lucey M.R. et al. Liver Transplantation for Alcoholic Liver Disease. Transplantation. 2016.
• Berenguer M. Last gasps of the hepatitis C virus dragon: Direct acting antiviral failures and hepatitis C virus–positive donors. Liver Transplantation. 2016; 22:47-51.
Hightlights
This year our group on “Hepatology & Liver Transplantation” obtained the IIS La Fe accreditation. We were also able to recruit staff members; one clinical researcher (Rio Hortega grant), one technician (La Fe Bankia Training Program) & finally one experimental researcher through CIBEREHD. The most relevant results have been published in 23 scientific articles. Two doctoral and one master thesis also have been presented. Currently, the group has 12 active projects (4 competitive projects, 8 privately financed) and 17 clinical trials.
EHD
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