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LEAD rESEArCHEr
Bosch Genover, Jaume
Hospital Clínico y Provincial de Barcelona
Villarroel, 170
08036 Barcelona
(+34) 93 2275400 (Ext. 3330) [email protected]
group Website
GROUP MEMBERS
Staff members: Campreciós Figueras, Genís | Gallego Pinos, Javier | García Caldero, Héctor | García Pras, Ester | Guixe Muntet, Sergi | Mejias Hernández, Marc | Orts Salvador, Lara | Saez Carceller, Rosa María | Torrijos Coma, Lidia
Associated members: Deulofeu Piguet, Ramón | Escorsell Mañosa, Ángeles | Fernández Iglesias, Anabel | Fernández Lobato, Mercedes | García-Pagán, Juan Carlos | Gracia Sancho, Jordi | Hernández Gea, Virginia
Main lines of research
• Factors regulating hepatic microcirculation in normal conditions and in cirrhosis
• Regulation of the transcription of protective genes of liver sinusoidal endothelium: relevance in the
pathophysiology of portal hypertension, prevention of complications of cirrhosis, in ex vivo liver
preservation, and liver aging.
• Interaction between different hepatic cell lines. Importance in maintaining the homeostasis of the liver
and on the progression / regression of cirrhosis and In the development of liver-on-a-chip devices.
• Angiogenesis in advanced chronic liver disease: function, regulation, and therapeutic potential
• Impact of obesity on chronic liver disease: pathogenic mechanisms and therapeutic implications.
• Molecular regulation of progression from hepatic steatosis to cirrhosis and liver cancer. Identification of
therapeutic targets.
• New methods of noninvasive evaluation in cirrhosis.
• Clinical trials of randomization of new treatments for portal hypertension and esophageal-gastric
variceal hemorrhage.
• Hepatic vascular diseases. Prognostic studies and new diagnostic methods.
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PROGRAMMES
P1