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Most relevant scientific articles
• Farre R.. Evaluating the esophageal epithelial integrity: More complex than it seems. American Journal of Gastroenterology. 2016;111(2):295-296.
• Bath P.M., Scutt P., Love J., Clave P., Cohen D., Dziewas R. et al. Pharyngeal Electrical Stimulation for Treatment of Dysphagia in Subacute Stroke: A Randomized Controlled Trial. Stroke. 2016.
• Mane N., Jimenez-Sabado V., Jimenez M.. BPTU, an allosteric antagonist of P2Y1 receptor, blocks nerve mediated inhibitory neuromuscular responses in the gastrointestinal tract of rodents. Neuropharmacology. 2016;110:376-385.
• Alvarez-Berdugo D., Rofes L., Casamitjana J.F., Padron A., Quer M., Clave P.. Oropharyngeal and laryngeal sensory innervation in the pathophysiology of swallowing disorders and sensory stimulation treatments. Annals of the New York Academy of Sciences. 2016;1380(1):104-120.
• Carrion S., Roca M., Costa A., Arreola V., Ortega O., Palomera E. et al. Nutritional status of older patients with oropharyngeal dysphagia in a chronic versus an acute clinical situation. Clinical Nutrition. 2016.
Hightlights
The Group has developed four groups of projects in 2016. The first, entitled ”Development of a sensory neuromodulation protocol to treat post-stroke oropharyngeal dysphagia”, has allowed the addition through a grant of a clinical neurophysiologist, raising the technical level of our studies on the CNS. The second
is the development and validation through a study pilot of the “Minimal-Massive Intervention” designed
to reduce the nutritional and respiratory complications and the readmission rate of elderly people with oropharyngeal dysphagia to General Hospitals and the development of a stable cooperation with Investen and CIBER on Frailty to disseminate and validate this therapeutic strategy. Our group also investigates
the relationship between frailty, anorexia and sarcopenia and has begun a new study on the relationship between obesity, sarcopenia and diabetes in elderly people and its treatment by physical exercise and dietary intervention. We have contributed to the development of two systematic reviews that have established clinical guidelines for the management of dysphagia; the first one after two years of interaction between two European scientific societies (ESSD/EUGMS), considering oropharyngeal dysphagia as a geriatric syndrome and setting the bases of its treatment; the second is a systematic review on the effect of changes rheology of the food bolus in patients with dysphagia, and establishes the optimal characteristics for the patients. Finally the fourth group of projects is a strategic action of called “Acces-ciberehd developing collaborative networks for basic research with human tissue in the area 2 of the ciberehd’ which has allowed three young researchers from the CIBER to lead and develop a network of 18 cooperative projects in basic research involving all the groups of the area 2 of the CIBEREHD. The group has completed its activity of 2016 with relevant basic studies on neurogastroenterology, multiple clinical trials and several relevant participations in international meetings.
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