Page 117 - CIBEREHD2016-ENG

Most relevant scientific articles
• Munoz-Gamez J.A., Lopez Viota J., Barrientos A., Carazo A., Sanjuan-Nunez L., Quiles-Perez R. et al. Synergistic cytotoxicity of the poly (ADP-ribose) polymerase inhibitor ABT-888 and temozolomide in dual-drug targeted magnetic nanoparticles. Liver International. 2016;35(4):1430-1441.
• Alonso S., Riveiro-Barciela M., Fernandez I., Rincon D., Real Y., Llerena S. et al. Effectiveness and safety of sofosbuvir-based regimens plus an NS5A inhibitor for patients with HCV genotype 3 infection and cirrhosis. Results of a multicenter real-life cohort. Journal of Viral Hepatitis. 2016.
• Ocete-Hita E., Salmeron-Fernandez M.J., Urrutia-Maldonado E., de Rueda P.M., Salmeron-Ruiz M., Martinez-Padilla M.C. et al. Analysis of Immunogenetic Factors in Idiosyncratic Drug-Induced Liver Injury in the Paediatric Population. Journal of Pediatric Gastroenterology and Nutrition. 2016.
• Munoz-Gamez J.A., Salmeron J., Ruiz-Extremera A. Hepatitis C during pregnancy, vertical transmission and new treatment possibilities. Medicina Clinica. 2016.
• Blanco-Reina E., Medina-Claros A.F., Vega-Jimenez M.A., Ocana-Riola R., Marquez-Romero E.I., Ruiz- Extremera A. Drug utilization pattern in children and off-label use of medicines in a pediatric intensive care unit. Medicina Intensiva. 2016;40(1):1-8.
Hightlights
In the year 2015, our research group has maintained active clinical and experimental projects related to our main line of research, “Viral Hepatitis in children and adults”:
• Project Intrasalud PI10/00717 entitled “Estudio de la variabilidad genética del VHC y la respuesta
inmune del hospedador en los pacientes tratados con interferón pegilado y ribavirina. Bases racionales
para la obtención de una vacuna terapéutica”.
• PI13/01925: Estudio de seguimiento de la transmisión vertical (TV) de los virus de la hepatitis C (VHC) y
de la hepatitis B (VHB): análisis de factores implicados.
• GLD15-00307: Validation study of biomarkers associated both with increased risk of mother-to-child
HCV transmission and with increased risk of persistent HCV infection in children vertically transmitted. In addition, we have been initiated two other projects: PI05152014, Junta de Andalucía, and PI1501361, FIS, related with the line of research “Relación de las Poblaciones de Pre-Adipocitos y el Infiltrado Inmunológico del Tejido Adiposo Con la Enfermedad del Hígado Graso No Alcohólico en Obesos Mórbidos”.
The collaborative research lines include the platform for the collection of data from patients with hepatitis B chronic (CIBERHEP), Hepatitis C (Hepa-C) national register and national register of Hepatocellular Carcinoma (HCC registration).
EHD
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